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An Atlas of Small Animal Ocular Surgery

為了解決Training for的問題，作者 這樣論述：

Rick became a Diplomate of the European College of Veterinary Ophthalmologists (DipECVO) in 2007. He is a Spanish national and followed his education in the US and the UK. He obtained a Bachelor’s degree in Biology in St. Thomas Aquinas College, in New York in 1994 and a DVM after attending Ross and

Louisiana State Universities in 1999. He commenced his specialty training in the US and later moved to the EU where he attended the Universidad Autónoma de Barcelona (UAB) to obtain his European veterinary qualification in 2002. Since, Rick obtained his RCVS certificate in ophthalmology (UK) and co

mpleted his residency training at the University of Glasgow and the Eye Veterinary Clinic, in Herefordshire, England, after which he obtained his DipECVO in 2007. Then, he headed the ophthalmology service in a private practice in England from 2006 until 2011. That same year he joined the Royal Veter

inary College of the University of London as a Lecturer to re-launch and lead the new Ophthalmology Service at the Queen Mother Hospital for Animals (QMHA).David graduated from the University of Edinburgh in 1992 and, after a period in general practice, completed a PhD at the University of Cambridge

in the molecular genetics of inherited eye diseases of dogs. Following this he moved to the University of Bristol for a three year clinical residency in veterinary ophthalmology. After this he was appointed Lecturer in Veterinary Ophthalmology at Bristol University Veterinary School, a post that he

held for three years before joining Davies Veterinary Specialists in October 2003 to jointly run their ophthalmology service. He holds both RCVS and European Diplomas in Veterinary Ophthalmology and is an RCVS recognised Specialist in Veterinary Ophthalmology and European Veterinary Specialist in O

phthalmology.

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技術型高中學生學習歷程檔案學習動機及其學習成效之關係研究-以桃竹苗地區為例

為了解決Training for的問題，作者羅筱恩 這樣論述：

摘要 本研究旨在探討公立技術型高中學生學習歷程檔案學習動機及其學習成效之關係研究。以108學年度入學就讀桃竹苗地區公立技術型高中學生為研究對象，採問卷調查法。發出8校900份問卷，回收有效650份問卷後經資料整理，再透過SPSS 20統計軟體進行資料處理與分析，探討技術型高中學生學習歷程檔案的學習動機及其學習成效之相關情形，進行敘述性統計及推論性統計之分析與討論。依據研究目的，本研究獲致結果如下：壹、桃竹苗地區學生學習歷程檔案以期望成分的學習動機認同度最高，以學習成果的學習成效認同度最高。貳、學生學習歷程檔案以女性學生、就讀家事類、苗栗地區以及上傳課程學習成果與多元學習表現件數多者的學

習動機認同度較高。參、學生學習歷程檔案以女性學生、就讀家事類、苗栗地區以及上傳課程學習成果與多元學習表現件數多者的學習成效認同度較高。肆、桃竹苗地區學生學習歷程檔案學習動機及其學習成效呈現高度正相關。關鍵字：技術型高中學生、學生學習歷程檔案學習動機、學生學習歷程檔案學習成效

Fundamentals of the Management of Urethral Strictures

為了解決Training for的問題，作者 這樣論述：

Christopher C R Chapple BSc MD FRCS (Urol), Professor of Urology and Consultant Urological Surgeon, Urology Research Department, The Royal Hallamshire Hospital, Sheffield, UK. Professor Chapple is the Adjunct Secretary General of the European Association of Urology in charge of all teaching of the A

ssociation throughout Europe. He teaches medical students and is actively involved in the training of sub-specialist registrars, as well as being responsible for all educational activities and guideline development in the European Association of Urology. He has a keen interest in evidence base and h

as been involved in leading reviews on pharmacotherapy of lower urinary tract dysfunction and more recently the NICE (National Institute for Health and Care Excellence) guideline development committee on the management of lower urinary tract symptoms.

An Integrated Approach For Uncovering Novel DNA Methylation Biomarkers For Non-small Cell Lung Carcinoma

為了解決Training for的問題，作者VAIBHAV KUMAR SUNKARIA 這樣論述：

Introduction - Lung cancer is one of primal and ubiquitous cause of cancer related fatalities in the world. Leading cause of these fatalities is non-small cell lung cancer (NSCLC) with a proportion of 85%. The major subtypes of NSCLC are Lung Adenocarcinoma (LUAD) and Lung Small Cell Carcinoma (LUS

C). Early-stage surgical detection and removal of tumor offers a favorable prognosis and better survival rates. However, a major portion of 75% subjects have stage III/IV at the time of diagnosis and despite advanced major developments in oncology survival rates remain poor. Carcinogens produce wide

spread DNA methylation changes within cells. These changes are characterized by globally hyper or hypo methylated regions around CpG islands, many of these changes occur early in tumorigenesis and are highly prevalent across a tumor type.Structure - This research work took advantage of publicly avai

lable methylation profiling resources and relevant comorbidities for lung cancer patients extracted from meta-analysis of scientific review and journal available at PubMed and CNKI search which were combined systematically to explore effective DNA methylation markers for NSCLC. We also tried to iden

tify common CpG loci between Caucasian, Black and Asian racial groups for identifying ubiquitous candidate genes thoroughly. Statistical analysis and GO ontology were also conducted to explore associated novel biomarkers. These novel findings could facilitate design of accurate diagnostic panel for

practical clinical relevance.Methodology - DNA methylation profiles were extracted from TCGA for 418 LUAD and 370 LUSC tissue samples from patients compared with 32 and 42 non-malignant ones respectively. Standard pipeline was conducted to discover significant differentially methylated sites as prim

ary biomarkers. Secondary biomarkers were extracted by incorporating genes associated with comorbidities from meta-analysis of research articles. Concordant candidates were utilized for NSCLC relevant biomarker candidates. Gene ontology annotations were used to calculate gene-pair distance matrix fo

r all candidate biomarkers. Clustering algorithms were utilized to categorize candidate genes into different functional groups using the gene distance matrix. There were 35 CpG loci identified by comparing TCGA training cohort with GEO testing cohort from these functional groups, and 4 gene-based pa

nel was devised after finding highly discriminatory diagnostic panel through combinatorial validation of each functional cluster.Results – To evaluate the gene panel for NSCLC, the methylation levels of SCT(Secritin), FOXD3(Forkhead Box D3), TRIM58(Tripartite Motif Containing 58) and TAC1(Tachikinin

1) were tested. Individually each gene showed significant methylation difference between LUAD and LUSC training cohort. Combined 4-gene panel AUC, sensitivity/specificity were evaluated with 0.9596, 90.43%/100% in LUAD; 0.949, 86.95%/98.21% in LUSC TCGA training cohort; 0.94, 85.92%/97.37 in GEO 66

836; 0.91,89.17%/100% in GEO 83842 smokers; 0.948, 91.67%/100% in GEO83842 non-smokers independent testing cohort. Our study validates SCT, FOXD3, TRIM58 and TAC1 based gene panel has great potential in early recognition of NSCLC undetermined lung nodules. The findings can yield universally accurate

and robust markers facilitating early diagnosis and rapid severity examination.